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Common symptoms include erythema dryness scaling fissuring edema itching and burning. The results indicate that TCR beta gene rearrangement analysis on PBL is a sensitive and highly specific technique that may contribute significantly to the differential diagnosis of patients with erythroderma.
Accordingly they develop a treatment plan for the disorder and any complications arising from it.
Exfoliative dermatitis differential diagnosis. 8 rows Exfoliative dermatitis or erythroderma is an erythematous scaly dermatitis involving. 28 rows Exfoliative dermatitis ED is a definitive term that refers to a scaling erythematous. Exfoliative dermatitis also known as erythroderma is an uncommon but serious skin disorder that family physicians must be able to recognize and treat appropriately.
Although the etiology is often unknown exfoliative dermatitis may be the. Sézary syndrome-clinical and histopathologic features differential diagnosis and treatment. Smith EV Shipley DR.
Severe exfoliative dermatitis caused by. Binhlam JQ King LE Jr. Exfoliative dermatitis or erythroderma is a clinical syndrome characterized by widespread erythema fine or large scales and desquamation of a significant portion of the body surface.
Appropriate management of the patient during the acute phase of erythroderma requires a firm understanding of the pathophysiology and consequences of this clinical syndrome. Exfoliative dermatitis must be treated by a doctor who performs a differential diagnosis to determine the underlying cause of the disorder. Accordingly they develop a treatment plan for the disorder and any complications arising from it.
The differential diagnosis for erythroderma in pediatric patients includes infections inflammatory skin diseases ichthyoses and congenital immunodeficiencies. This topic will discuss the clinical manifestations diagnosis and treatment of erythroderma in adults. Erythroderma in neonates and infants and Sézary syndrome are discussed separately.
Erythroderma is the term used to describe intense and usually widespread reddening of the skin due to inflammatory skin disease. It often precedes or is associated with exfoliation skin peeling off in scales or layers when it may also be known as exfoliative dermatitis ED. Erythroderma and exfoliative dermatitis are largely synonymous.
However erythroderma is the preferred term and is currently in vogue. The former is characterized by extensive and pronounced erythema coupled with perceptible scaling whereas the latter is conspicuous by the presence of widespread erythema and marked scaling. What is the differential diagnosis with keratolysis exfoliativa.
Keratolysis exfoliativa is distinct from the following conditions. Various forms of hand dermatitis including contact dermatitis Pompholyx an itchy form of eczema in which there are small fluid-filled blisters. As described in Table 3 major differential diagnosis of EM and SJSTEN are 1 staphylococcal scalded skin syndrome SSSS 2 autoimmune blistering diseases and disseminated fixed bullous drug eruption 3 others severe delayed DHR 6 70 82 4 Graft versus host disease.
Keratolysis exfoliativa KE is a palmoplantar eruption of air-filled bullae on an erythematous base which results in lamellar peeling with hallmark superficial collarettes of scale. It is distinct from other diseases of volar skin such as dyshidrosis contact dermatitis. Common diseases that can lead to exfoliative dermatitis are autoimmune disorders psoriasis atopic dermatitis pityriasis rubra pilaris systemic diseases leukemia Hodgkin disease lung cancer HIV infection or drugs such as penicillin barbiturates codeine etc.
In the latter case if an affected individual stops the medication they will recover unless they have already sustained a complication. Cheilitis is an acute or chronic inflammation of the lips. It usually involves the lip vermilion and the vermilion border but the surrounding skin and the oral mucosa may also be affected 1.
Common symptoms include erythema dryness scaling fissuring edema itching and burning. Cheilitis may be caused by a multiplicity of endogenous or exogenous factors the most common of which are atopic dermatitis. The results indicate that TCR beta gene rearrangement analysis on PBL is a sensitive and highly specific technique that may contribute significantly to the differential diagnosis of patients with erythroderma.