Non reward attractor theory of depression

Fingerprint Dive into the research topics of Commentary on A non-reward attractor theory of depression. The theory proposed is that in depression this lateral orbitofrontal cortex non-reward system is more easily triggered and maintains its attractor-related firing for longer.

A non-reward attractor theory of depression in which the lateral orbitofrontal cortex attractor network system for non-reward maintains its activity for too long.

Non reward attractor theory of depression. A non-reward attractor theory of depression 1. Major depressive disorder is ranked by the World Health Organization as the leading cause of. A non-reward attractor theory of depression.

It is well established that not receiving expected reward or receiving. Not receiving reward can produce depression. The theory proposed is that in depression this lateral orbitofrontal cortex non-reward system is more easily triggered and maintains its attractor-related firing for longer.

This triggers negative cognitive states which in turn have positive feedback effects on the orbitofrontal cortex non-reward system. The non-reward attractor theory of depression describes this mood disorder as originating from a neuronal dysfunction that arises from increased vulnerability of a cortical network that detects failure to receive an expected reward. A non-reward attractor theory of depression is proposed based on the operation of the lateral orbitofrontal cortex and supracallosal cingulate cortex.

The orbitofrontal cortex contains error neurons that respond to non-reward for many seconds in an attractor state that maintains a memory of the non-reward. A non-reward attractor theory of depression is proposed based on the operation of the lateral orbitofrontal cortex and supracallosal cingulate cortex. The orbitofrontal cortex contains error neurons that respond to non-reward for many seconds in an attractor state that maintains a memory of the non-reward.

The theory proposed is that in depression this lateral orbitofrontal cortex non-reward system is more easily triggered and maintains its attractor-related firing for longer. This triggers negative cognitive states which in turn have positive feedback top-down effects on the orbitofrontal cortex non-reward. A non-reward attractor theory of depression is proposed based on the operation of the lateral orbitofrontal cortex and supracallosal cingulate cortex.

The orbitofrontal cortex contains error neurons that respond to non-reward for many seconds in an attractor state that maintains a memory of the non-reward. The non-reward attractor theory of depression describes this mood disorder as originating from a neuronal dysfunction that arises from increased vulnerability of a cortical network that detects failure to receive an expected reward. From an evolutionary standpoint the concept that the cerebral cortex determines susceptibility to mood disorders.

In depression the lateral orbitofrontal cortex non-reward attractor network system is over-connected and has increased sensitivity to non-reward providing a new approach to understanding. Abstract The nonreward attractor theory of depression describes this mood disorder as originating from a neuronal dysfunction that arises from increased vulnerability of a cortical network that detects failure to receive an expected reward. From an evolutionary standpoint the concept that the cerebral cortex determines susceptibility to mood disorders is open to criticism.

A non-reward attractor theory of depression. Neuroscience and Biobehavioral Reviews 68. Reward systems in the brain and nutrition.

Annual Review of Nutrition 36. A computational theory of hippocampal function and tests of the theory. The theory proposed is that in depression this lateral orbitofrontal cortex non-reward system is more easily triggered and maintains its attractor-related firing for longer.

This triggers negative cognitive states which in turn have positive feedback top-down effects on the orbitofrontal cortex non-reward. Increased activity in a lateral orbitofrontal cortex non-reward area provides a new attractor-related approach to understanding and treating depression. Consistent with the theory the lateral orbitofrontal cortex has increased functional connectivity in depression and the medial orbitofrontal cortex involved in reward has decreased functional connectivity in depression.

A non-reward attractor theory of depression in which the lateral orbitofrontal cortex attractor network system for non-reward maintains its activity for too long. And the medial orbitofrontal cortex reward system is less responsive 559 572 579 626 B12 B13 B14 B15. The theory is supported by a.

Fingerprint Dive into the research topics of Commentary on A non-reward attractor theory of depression. A proposal to include the habenula connection. Together they form a unique fingerprint.

Sort by Weight Alphabetically. The roles of the orbitofrontal cortex via the habenula in non-reward and depression and in the responses of serotonin and dopamine neurons. Neuroscience and Biobehavioral Reviews 2017.

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